个人简介

研究工作经历

2011.04-至今,苏州大学 农业生物技术与生态研究院 副院长

2021.06-至今,苏州大学 苏州医学院凯发唯一官方网站 教授(二级)/博导

2013.03-2021.05,苏州大学 医学部凯发唯一官方网站 教授(二级,2017-)/博导

2008.02-2013.02,苏州大学 医学部凯发唯一官方网站 应用生物学系 主任/教授/博导

2005.06-2008.01,苏州大学 生命科学学院 生物资源与环境科学系 主任/教授/博导

2001.11-2005.05,苏州大学 农业科学与技术学院 生物资源与环境科学系 主任/教授(2002-)/博导(2004-)

2001.04-2001.10,Department of Applied Biology, Faculty of Texyile Science and Technology, Shinshu University, JAPAN. Senior Visiting Scholar

1999.09-2001.03,Zuhrah Pelangi Sdn. Bhd., 93150 Kuching, Sarawak, MALAYSIA. CTO

1997.07-1999.08,苏州大学 生物技术学院 蚕学系副主任/副教授

1995.10-1996.10,Faculty of Agriculture, Tottori University, JAPAN. Visiting fellow

1994.10-1995.09,Faculty of Agriculture, Tottori University, JAPAN. Visiting Scholar

1982.09-1994.09,苏州大学(原苏州蚕专)助手、助教、讲师


教育经历

1994.02-1997.06,浙江大学(原浙江农业大学)博士研究生

1986.09-1988.12,浙江大学(原浙江农业大学)硕士研究生

1979.09-1982.06,苏州大学(原苏州蚕专)


社会兼职

2011-至今,中国中西医结合学会 时间生物医学专业委员会 常委

2020-2023,中国细胞生物学会 生物节律分会 委员

2004-2018,江苏省昆虫学会 常务理事

2016-2022,江苏省蚕桑学会 常务理事

2012-至今,浙江省(2011-)、重庆市(2013-)、广东省(2015-)、山东省(2016-)、江西省(2017-)、河北省(2018-)、贵州省(2020-)、甘肃省(2021-)、上海市(2021-)科技厅(局) 科技咨询专家

2016-至今,Scientific Reports,Editorial Board Member

2023-至今,Zoological ResearchEditorial review board member

2000-2003,Hatada International Silk Research andTraining Center. Phnom Penh,CAMBODIA. Chief advisor

2018-至今,Lao-China Green Silk Research Center (GSC).Vientiane, LAOS. CTO


研究领域

1. 发育的分子遗传及调控机制

2. 生物医学替代实验动物


基本信息

头像

徐世清  

职称:   教授

院部/部门:   苏州医学院凯发唯一官方网站

学历:   研究生

学位:   博士

毕业学校:   (原)浙江农业大学

毕业专业:  

联系方式

通讯地址:   苏州市仁爱路199号苏州大学独墅湖校区702-2428

邮政编码:   215123

电子邮箱:   szsqxu@suda.edu.cn

联系电话:   65880185

传真号码:  

办公地点:   苏州大学独墅湖校区702-2428

Copyright © 2011-2014苏州大学版权所有 苏州大学信息化建设与管理中心技术支持

科学研究

主要研究动物色素形成、蛋白质高效合成、生物钟、性别的分子调控机制及应用技术开发,研究抗生素筛选、抗病和增强免疫力的活性成分筛选、代谢性疾病先导化合物的发现以及药物的毒理研究等无脊椎模式动物家蚕作为模式生物的关键科学问题。近年承担的主要研究项目:


(1)国家自然科学基金,基于昼夜节律钟基因Period敲除突变体家蚕的生物钟与内分泌激素协同调控滞育的机制研究32172794),2022-2025(项目主持人)

(2)国家自然科学基金,基于组织发育模型的转基因家蚕后部丝腺蛋白质合成和分泌效率的调控机制研究(31972625),2020-2023(项目主持人)

(3)国家自然科学基金,基于昼夜节律钟基因突变体的家蚕生物钟与滞育代谢的整合机制研究(31672492),2017-2020(项目主持人)

(4)国家自然科学基金,基于组织退化发育模型的家蚕丝腺高效丝蛋白质分泌功能的转化调控机制研究(31472149),2015-2018(项目主持人)

(5)国家自然科学基金,基于家蚕昼夜节律生物钟信号途径基因发掘的滞育诱导授时信号输入机制研究(31172264),2012-2015(项目主持人) 

(6)国家863重大/主题项目课题,动物分子与细胞育种技术研究(2011AA100306),2011-2015(团队负责人)

(7)国家科技支撑计划,天然彩色茧家蚕新品种选育及蚕丝蛋白资源深加工关键技术研究与产业化开发(2007BAD72B01),2007-2010(课题主持人)

(8)国家自然科学基金,基于Ea4与Sod基因互作的滞育生物钟分子调控机制研究(30771632),2008-2010(项目主持人)

(9)国家自然科学基金,家蚕滞育生物钟蛋白质EA4的分子作用机理研究(30371086),2004-2006(项目主持人)

(10)国家973计划课题,家蚕生物工厂及基因组应用的拓展研究(2005CB121005),2005-2010(学术骨干)

(11)国家863重大项目课题,家蚕资源评价的分子基础及重要功能基因克隆研究(2004AA2Z1020),2004-2005(学术骨干)

(12)江苏省重大成果转化项目,家蚕天然彩色茧研发及产品产业化(BA2007074),2007-2010(项目共同主持人)

(13)江苏省重大科技支撑与自主创新专项引导资金项目,家蚕分子育种技术创新(BE2011327-1),2011-2014(项目主持人)

(14)江苏省重点研发计划项目,新功能丝蛋白生产家蚕新资源研制与优质、抗性品种培育(BE2015317),2015-2019(项目主持人)

(15)江苏省自然科学基金,以无脊椎模式动物家蚕为材料的实验动物替代研究(BK2011298),2012-2015(项目共同主持人)

(16)江苏省科技挂县强农富民计划,(江苏省财政厅苏财农[2009]44号,[2010]82号,[2011]65号,[2012]56号,[2013]15号, [2014]27号,[2015]35号,[2016]28号,[2017]53号,[2018]110号、;江苏省农业委员会(农业厅)苏农计[2009]44号,[2010]40号,[2011]52号,[2012]83号,[2013]33号,[2014]16号,[2015]34号,[2016]18号,[2017]22号;[2018]31号;2009-2019(项目主持人)

(17)江苏省渔业科技项目,优质中华绒螯蟹鉴别技术集成创新与应用(Y2017-5),2017-2019(首席专家)

  (18)江苏省优势学科创新团队,创新丝蛋白纤维材料的分子遗传设计 2011-2018(团队负责人)

(19)江苏省产业技术研究院重点项目,高效集约化现代养蚕关键技术研究及产业化(SD1501),2015-2018(项目主持人)

(20)老挝国家科技部、江苏省产业技术研究院重大项目,中国-老挝绿色丝绸中心(3ZCY1801),2018-2020(项目主持人)


科研团队

1. 在站博士后

邱剑丰,王光,崔文沼,李萍

2. 在读博士研究生

姜桂华(基础医学);戴泰明(畜牧学);彭如及(畜牧学);罗程(特种经济动物饲养

3. 在读硕士研究生

马璐(畜牧),杨佳萌(畜牧);王玉国(动物遗传育种与繁殖),刘精斌(畜牧),杨宝成(畜牧);Yasir khan(遗传学),王晨晨(特种经济动物饲养),宋垚乐(畜牧),杜江晗(畜牧)

Copyright © 2011-2014苏州大学版权所有 苏州大学信息化建设与管理中心技术支持

论文

由中国科学技术出版社等出版编著和著作5部,国内外杂志发表论文180余篇,在国际学术会议发表论文120多篇。近年发表的主要论文(*通讯作者):

  1. Wang G, Xu XX, Ma L, Yang JM, Yang BC, Peng RJ, Pan ZH, Sima YH, Xu SQ*. Nonsteaming method improves the nutritional value and utilization efficiency of silkworm artificial diets. J Econ Entomol. 2024 Jan 24:toae014. doi: 10.1093/jee/toae014. Epub ahead of print. PMID: 38266252.

  2. Wang G, Ding X, Yang J, Ma L, Sun X, Zhu R, Lu R, Xiao Z, Xing Z, Liu J, Pan Z, Xu S, Sima Y*. Effects of Habitual Dietary Change on the Gut Microbiota and Health of Silkworms. INT J MOL SCI. 2024; 25(3):1722. https://doi.org/10.3390/ijms25031722

  3. Wang G, Jiang G, Peng R, Wang Y, Li J, Sima Y, Xu S*. Multi-omics integrative analysis revealed characteristic changes in blood cell immunity and amino acid metabolism in a silkworm model of hyperproteinemia. Int J Biol Macromol. 2023 Dec 19;258(Pt 1):128809. doi: 10.1016/j.ijbiomac.2023.128809. Epub ahead of print. PMID: 38128801.(Top Journal)

  4. Jiang GH, Wang G, Luo C, Wang YF, Qiu JF, Peng RJ, Sima YH, Xu SQ*. Mechanism of hyperproteinemia-induced damage to female reproduction in a genetic silkworm model. iScience. 2023 Sep 9;26(10):107860. doi: 10.1016/j.isci.2023.107860. PMID: 37752953; PMCID: PMC10518704. https://www.sciencedirect.com/science/article/pii/S2589004223019375?via%3Dihub

  5. Yuan XN, Luo C, Zhao QF, Zhong SY, Hang Q, Dai TM, Pan ZH, Sima YH, Qiu JF*, Xu S*. The clock gene Cryptochrome 1 is involved in the photoresponse of embryonic hatching behavior in Bombyx mori. Arch Insect Biochem Physiol. 2023 Aug 15:e22046. doi: 10.1002/arch.22046. Epub ahead of print. PMID: 37583246.https://onlinelibrary.wiley.com/doi/10.1002/arch.22046.

  6. Jian-Feng Qiu, Cheng Luo, Li-Hua Ren, Wei Li, Tai-Ming Dai, Guang Wang, Xiao-Ning Sun, Kou-Chang Chong Moua, Yang-Hu Sima and Shi-Qing Xu.Black soldier fly larvae replace traditional iced trash fish diet to enhance the delicious flavor of Chinese mitten crab (Eriocheir sinensis). Front Mar Sci. 09 January 2023. Sec. Aquatic Physiology. Volume 9 - 2022 | doi: 10.3389/fmars.2022.1089421.

  7. Wang Y, Shi M, Yang J, Ma L, Chen X, Xu M, Peng R, Wang G, Pan Z, Sima Y, Xu S*. Sericin Ser3 Ectopic Expressed in Posterior Silk Gland Affects Hemolymph Immune Melanization Response via Reducing Melanin Synthesis in Silkworm. Insects. 2023; 14(3):245. https://doi.org/10.3390/insects14030245.

  8. Qiu J, Dai T, Tao H, Li X, Luo C, Sima Y, Xu S*. Inhibition of Expression of the Circadian Clock Gene Cryptochrome 1 Causes Abnormal Glucometabolic and Cell Growth in Bombyx mori Cells. Int J Mol Sci. 2023 Mar 12; 24(6):5435. https://doi.org/10.3390/ijms2406543.

  9. Qiu J, Dai T, Luo C, Cui W, Liu K, Li J, Sima Y, Xu S*. Circadian clock regulates developmental time through ecdysone and juvenile hormones in Bombyx mori. Insect Mol Biol. 2023 Feb 23. doi: 10.1111/imb.12835. Epub ahead of print. PMID: 36815346.(Top Journal)

  10. Yuan Q, Sun X, Lu R, Qu Z, Ding X, Dai T, Qiu J, Tan Y, Zhu R, Pan Z, Xu S, Sima Y*The LIM Domain Protein BmFHL2 Inhibits Egg Production in Female Silkworm, Bombyx moriCells. 2023 Jan 31;12(3):452. doi: 10.3390/cells12030452. PMID: 36766794; PMCID: PMC9913792.

  11. Chen X, Wang Y, Wang Y, Li Q, Liang X, Wang G, Li J, Peng R, Sima Y, Xu SQ*. Ectopic expression of sericin enables efficient production of ancient silk with structural changes in silkworm. Nat Commun. 2022 Oct 22;13(1):6295. doi: 10.1038/s41467-022-34128-5. PMID: 36273007; PMCID: PMC9588020(Top Journal)

  12. Sun X, Yuan Q, Du B, Jin X, Huang X, Li Q, Zhong Y, Pan Z, Xu SQ, Sima Y *. Relationship between Changes in Intestinal Microorganisms and Effect of High Temperature on the Growth and Development of Bombyx mori Larvae. Int J Mol Sci. 2022 Sep 7;23(18):10289. doi: 10.3390/ijms231810289. PMID: 36142203; PMCID: PMC9499401. (Top Journal)

  13. Jian-Feng Qiu, Wen-Zhao Cui, Qiang Zhang, Tai-Ming Dai, Kai Liu, Jiang-Lan Li, Yu-Jun Wang, Yang-Hu Sima and Shi-Qing Xu*. Temporal transcriptome reveals that circadian clock is involved in the dynamic regulation of immune response to bacterial infection in Bombyx mori. Insect Sci2022 Apr 21; doi: 10.1111/1744-7917.13043.PMID: 35446483.(Top Journal)

  14. Chen X, Ye A, Wu X, Qu Z, Xu S, Sima Y, Wang Y, He R, Jin F, Zhan P, Cao J*, Zhou W* . Combined analysis of silk synthesis and hemolymph amino acid metabolism reveal key roles for glycine in increasing silkworm silk yields.Int J Biol Macromol. 2022 Jun 1; 209(Pt B):1760-1770. doi: 10.1016/j.ijbiomac.2022.04.143.(Top Journal)

  15. Guang Wang, Yong-Feng Wang, Jiang-Lan Li, Ru-Ji Peng, Xin-Yin Liang, Xue-Dong Chen, Gui-Hua Jiang, Jin-Fang Shi, Yang-Hu Si-Ma, Shi-QingXu *Mechanism of hyperproteinemia-induced blood cell homeostasis imbalance in an animal model. Zool Res. 2022 May 18; 43(3):301-318. doi: 10.24272/j.issn.2095-8137.2021.397. PMID: 35312240. (Top Journal)

  16. Cui WZ, Qiu JF, Dai TM, Chen Z, Li JL, Liu K, Wang YJ, Sima YH, Xu SQ *.Circadian clock gene period contributes to diapause via GABAeric-Diapause hormone pathway in Bombyx mori. Biology (Basel)2021 Aug 30; 10(9):842.  doi.org/10.3390/biology10090842.

  17. Hou M, Dai TM, Liang XY, Zhang SX, Cui WZ, Qiu JF, Sima YH, Cui WZ*Xu SQ *.Bombyx mori can synthesize ascorbic acid through the L-gulose pathway to varying degrees depending on developmental stage. Arch Insect Biochem Physiol. 2021 Mar 15; e21783. doi: 10.1002/arch.21783.

  18. Wang YF, Wang G, Li JL, Qu YX, Liang XY, Chen XD, Li QY, Sima YH, Xu SQ *Influence of Hyperproteinemia on Insect Innate Immune Function of the Circulatory System in Bombyx mori.Biology (Basel). 2021 Feb 3; 10(2):112. doi: 10.3390/biology10020112.

  19. He Y, Xu X, Qiu JF, Yin WM, Sima YH, Xu SQ *Bombyx mori used as a fast detection model of liver melanization after a clinical drug - Acetaminophen exposure. ASPEN. 2020, 23(1): 177-185. doi.org: 10.1016/j.aspen.2019.11.009

  20. Zhang YH, Shi MJ, Li KL, Xing R, Chen ZH, Chen XD, Wang YF, Liu XF, Liang XY, Sima YH, Xu SQ *. Impact of adding glucose-coated water-soluble silver nanoparticles to the silkworm larval diet on silk protein synthesis and related properties. J Biomater Sci Polym Ed. 2020 Feb; 31(3):376-393. doi: 10.1080/09205063.2019.1692642.

  21. Wang YF, Chen XD, Wang G, Li QY, Liang XY, Shi MJ, Sima YH, Xu SQ*. Influence of hyperproteinemia on reproductive development in an invertebrate model. Int J Biol Sci. 2019, 15(10): 2170-2181 (Featured in the cover).

  22. Qiu JF, Li X, Cui WZ, Liu XF, Tao H, Yang K, Dai TM, Sima YH,Xu SQ*. Inhibition of Period Gene Expression Causes Repression of Cell Cycle Progression and Cell Growth in the Bombyx mori Cells. Front Physiol. 2019 May 3, 10:537. doi: 10.3389/fphys.2019.00537

  23. Dong HL, Zhang SX, Chen ZH,Tao H, Li X, Qiu JF, Cui WZ, Sima YH, Cui WZ*, Xu SQ*. Differences in gutmicrobiota between silkworms (Bombyx mori) reared on fresh mulberry (Morus alba var.multicaulis) leaves or an artificial diet. Rsc Advances. 2018, 8(46):26188-26200.

  24. Chen XD, Wang YF, Wang YL, Li QY, Ma HY, Wang L, Sima YH, Xu SQ*. Induced hyperproteinemia and its effects on the remodeling of fat bodies in silkworm, Bombyx mori. Front Physiol. 2018 Mar 29; 9:302. doi: 10.3389/fphys.2018.00302. 

  25. Tao H, Du B, Wang H, Dong H, Yu D, Ren L, Sima Y*, Xu SQ*. Intestinal microbiome affects the distinctive flavor of Chinese mitten crabs in commercial farms. Aquaculture. 2018, 483: 38–45(Top Journal)

  26. Xing R, Zhang YH, Zhou YF, Chen XD, Li KL, Su YY, Wu SC, Sima YH, Zhang KQ, He Y*, Xu SQ*. A comparison of the toxic effects of fluorescent silicon nanoparticles in males and females of the silkworm, Bombyx mori.Sci Adv Mater. 2018, 10(3), 315–323. https://doi.org/10.1166/sam.2018.3225

  27. Dong HL, Zhang SX, Tao H, Chen ZH, Li X, Qiu JF, Cui WZ, Sima YH, Cui WZ*, Xu SQ*. Metabolomics diferences between silkworms (Bombyx mori) reared on fresh mulberry (Morus) leaves or artificial diets. Sci Rep. 2017; 7: 10972 | DOI:10.1038/s41598-017-11592-4

  28. Tao H, Li X, Qiu JF, Cui WZ, Sima YH, Xu SQ*. Inhibition of expression of the circadian clock gene Period causes metabolic abnormalities including repression of glycometabolism in Bombyx mori cells. Sci Rep. 2017 Apr 10; 7:46258. doi: 10.1038/srep46258.

  29. Kai-Le Li, Yun-Hu Zhang, Rui Xing, Yan-Feng Zhou, Xue-Dong Chen, Hao Wang, Bin Song, Yang-Hu Sima, Yao He*, Shi-Qing Xu*. Different toxicity of cadmium telluride, silicon, and carbon nanomaterials against hemocytes in silkworm, Bombyx mori. RSC Adv. 2017, 7: 50317–50327

  30. Tao H, Li X, Qiu JF, Liu HJ, Zhang DY, Chu F, Sima YH, Xu SQ*. The light cycle controls the hatching rhythm in Bombyx mori via negative feedback loop of the circadian oscillator. Arch Insect Biochem Physiol. 2017; 96(2). doi:10.1002/arch.21408.

  31. Yan SQ, Xing R, Zhou YF, Li KL, Su YY, Qiu JF, Zhang YH, Zhang KQ, He Y*, Lu XP*, Xu SQ*. Reproductive toxicity and gender differences induced by cadmium telluride quantum dots in an invertebrate model organism. Sci Rep. 2016 Sep 27; 6:34182. doi: 10.1038/srep34182.

  32. Xing R, Chen XD, Zhou YF, Zhang J, Su YY, Qiu JF, Sima YH, Zhang KQ*,He Y*, Xu SQ*. Targeting and retention enhancement of quantum dots decorated with amino acids in an invertebrate model organism. Sci Rep. 2016 Jan 25; 6:19802.doi: 10.1038/srep19802.

  33. Xing R, Li KL, Zhou YF, Su YY, Yan SQ, Zhang KL, Wu SC, Sima YH, Zhang KQ*, He Y*, Xu SQ*. Impact of fluorescent silicon nanoparticles on circulating hemolymph and hematopoiesis in an invertebrate model organism. Chemosphere. 2016 Sep; 159: 628-37. doi: 10.1016/j. chemosphere. 2016.06.057.

  34. Wang H, Wang Y, Wu C, Tao H, Chen X, Yin W, Sima Y, Wang Y*, Xu SQ*. Changes in 30K protein synthesis during delayed degeneration of the silk gland by a caspase-dependent pathway in a Bombyx (silkworm) mutant.J Comp Physiol B. 2016Aug; 186(6):689-700. doi: 10.1007/s00360-016-0990-4

  35. Ji MM, Liu AQ, Sima YH, Xu SQ*. 20-Hydroxyecdysone stimulates nuclear accumulation of BmNep1, a nuclear ribosome biogenesis-related protein in the silkworm, Bombyx mori. Insect Mol Biol. 2016 Jun 22. doi: 10.1111/imb.12248.

  36. Fang Y, He Y, Wang H, Yan S, Xing R, Yin W, Sima Y, Xu SQ*. Hematopoiesis toxicity induced by4-methylumbelliferon determined in an invertebrate model organism. Drug Chem Toxicol. 2016; 39(2):199-205. doi: 10.3109/01480545.2015.1079915.

  37. Chu F, Qiu JF, Tao H, Li X, Shu MY, Liu HJ, Sima Y, Xu SQ*. Impact of cyclical changes in temperature on circadian clock gene expression in Bombyx BmN cells. Arch Insect Biochem Physiol. 2016Mar; 91(3):175-86. doi: 10.1002/arch.21317.

  38. Wang H, Wang L, Wang Y, Tao H, Yin W, Sima Y, Wang Y*, Xu SQ*. High yield exogenous HPL protein production in the Bombyx mori silk gland provides novel insight into recombinant expression systems. Sci Rep. 2015 Sep 15; 5:13839. doi: 10.1038/srep13839.

  39. Wang H, Fang Y, Wang L, Zhu W, Ji H, Wang H, Xu SQ, Sima Y*. Heterosis and differential gene expression in hybrids and parents in Bombyx mori by digital gene expression profiling. Sci Rep. 2015 Mar 4; 5:8750. doi: 10.1038/srep08750.

  40. Tao H, Liu HJ, Cheng YQ, Sima YH, Yin WM, Xu SQ*. Parental environmental exposure leads to glycometabolic disturbances that affect fertilization of eggs in the silkworm Bombyx mori: the parental transcript legacy. Comp Physiol B. 2015, 185(1):47-55. DOI10.1007/s00360-014-0864-6.

  41. Yuan HX*, Xu SQ, Sima YH. Changes in malondialdehyde content, antioxidative enzyme activity, and their gene expression in gonads during different developmental stages of4-n-nonylphenol-treated Bombyx mori (Lepidoptera: Bombycidae).  Ann Entomol Soc Am. 2015, 108(2):193-200.

  42. Liu T, Xing R, Zhou YF, Zhang J, Su YY, Zhang KQ*, He Y*,Sima YH*, Xu SQ*. Hematopoiesis toxicity induced by CdTe quantum dots determined in an invertebrate model organism. Biomaterials. 2014, 35(9):2942-51.doi: 10.1016 (Top Journal).

  43. Zhuo W, Chu F, Kong L, Tao H, Sima Y, Xu SQ*. Chitin Synthase B: a midgut-specific gene induced by insect hormones and involved in food intake in Bombyx mori larvae. Arch Insect Biochem Physiol. 2014, 85(1):36-47. doi: 10.1002.

  44. Fang Y, Wang H, Zhu W, Wang L, Liu H, He Y, Xu X, Yin W, Sima Y, Xu SQ*. Antioxidative capacity in the fat body of Bombyx mori is increased following oral administration of 4-methylumbelliferone.Comp Biochem Physiol C Toxicol Pharmacol. 2014, 159:31-37. doi: 10.1016.

  45. Fang Y, Wang H, Zhu W, Wang L, Liu H, Xu X, Yin W, Sima Y*, Xu SQ*. Antioxidative properties of 4-methylumbelliferone are related to antibacterial activity in the silkworm (Bombyx mori) digestive tract. Comp Physiol B. 2014, 184(6):699-708.doi: 10.1007/s00360-014-0840-1.

  46. Yin WM, Xu X, He Y, Wei GB, Sima YH, Xu SQ*. Metabonomic analysis of Bombyx mori treated with acetaminophen. J Insect Sci. 2014 Jan 1; 14.pii: 225. doi: 10.1093.

  47. Zhuo WW, Fang Y, Kong LF, Li X, Sima YH, Xu SQ*. Chitin synthase A: a novel epidermal development regulation gene in the larvae of Bombyx mori. Mol Biol Rep. 2014, 41(7):4177-86. dio:10.1007/s11033-014-3288-1.

  48. Wang H, Fang Y, Bao Z, Jin X, Zhu W, Wang L, Liu T, Ji H, Wang H, Xu SQ, Sima Y*. Identification of a Bombyx mori gene encoding small heat shock protein BmHsp27.4 expressed in response to high-temperature stress. Gene. 2014, 538(1):56-62. doi: 10.1016.

  49. Wang H, Fang Y, Wang L, Zhu W, Ji H, Wang H, Xu SQ, Sima Y*. Transcriptome analysis of the Bombyx mori fat body after constant high temperature treatment shows differences between the sexes. Mol Biol Rep. 2014, 41(9):6039-6049.dio: 10.1007/s11033-014-3481-2.

  50. Ji MM, Liu AQ, Gan LP, Xing R, Wang H, Sima YH, Xu SQ*. Functional analysis of 30K proteins during silk gland degeneration by a caspase-dependent pathway in Bombyx. Insect Mol Biol. 2013, 22(3):273-83. doi: 10.1111.

  51. Xu X, Wang M, Wang Y, Sima Y, Zhang D, Li J, Yin W, Xu SQ*. Green cocoons in silkworm Bombyx mori resulting from the quercetin 5-O-glucosyltransferase of UGT86, is an evolved response to dietary toxins. Mol Biol Rep. 2013; 40(5):3631-9.doi:10.1007/s11033-012-2437-7.

  52. Gan L, Zhuo W, Li J, Wang Y, Sima Y, Xu SQ*. A novel Cph-like gene involved in histogenesis and maintenance of midgut in Bombyx mori.Pest Manag Sci. 2013, 69(12): 1298-1306. doi: 10.1002/ps.3501.

  53. Yuan HX, Xu X, Sima YH, Xu SQ*. Reproductive toxicity effects of 4-nonylphenol with known endocrine disrupting effects and induction of vitellogenin gene expression in silkworm, Bombyx mori. Chemosphere. 2013, 93(2):263-268. doi: 10.1016. (Top Journal).

  54. Yuan HX,Sima YH,Xu SQ*. Differential effects of 4-n-NonylphenolonGlutathione, glutathione S-transferase, and glutathione peroxidase on Gonads indifferent developmental stages in the Bombyx mori (Lepidoptera: Bombycidae).Ann Entomol Soc Am. 2013, 106(6):832-839.

  55. Fang LX, Xin Rui, Che Y, Xu SQ*. Expression of sex-related genes in chicken embryos during male-to-female sex reversal exposure to diethylstilbestrol.J Integr Agr. 2013, 12(1):101-108.




荣誉奖励

Copyright © 2011-2014苏州大学版权所有 苏州大学信息化建设与管理中心技术支持

开授课程

1. 发育生物学(研究生、本科生课程)

2. 发育的奥秘与原理(本科生新生研讨课程)

3. 动物生殖生理与分子调控(博士研究生课程)

4. 现代动物遗传育种原理与技术(硕士研究生课程)

招生信息

1.博士后

1)基础医学博士后流动站动物疾病模型方向

2)畜牧学博士后流动站动物发育分子遗传方向

2.学术型博士研究生招生专业

(1)畜牧学 动物遗传育种与繁育(动物发育分子遗传方向)(农学学位)

2畜牧学 特种经济动物饲养(蚕发育与分子遗传方向)(农学学位)

3.学术型硕士研究生招生专业

(1)畜牧学 动物遗传育种与繁育(动物发育与分子遗传方向)

2畜牧学 特种经济动物饲养(蚕发育与分子遗传方向)

4.专业硕士

  畜牧 养殖学(MAE




Copyright © 2011-2014苏州大学版权所有 苏州大学信息化建设与管理中心技术支持
  • 荣誉奖励(旧版)

    科研成果  

    主持完成的项目获得20余项成果奖励,动物色素调控机理和应用研究成果2006年入选江苏省十五重大创新成果和苏州大学211”工程十五建设标志性成果,家蚕遗传分子设计和种质资源创新成果2020年入选苏州大学建校120周年标志性成果,并在Nature专题介绍。成果转化产品获3个国家金奖,获国家发明专利授权17件。主持编制国家标准2个、江苏省地方标准2个,育成动物新品种6代表奖项有

      

    1)江苏省科学技术奖 一等奖2013.021排名  

    2)香港桑麻基金会 科技奖 一等奖2012.09独立获奖  

    3)中国纺织工业协会科技成果奖(省部级)一等奖2011.101排名  

    4)江苏省科技进步奖 三等奖2项,2002.021994.101排名  

    5)江苏省科学技术奖 三等奖2项,2012.022009.022排名  

    6)江苏省“十五”重大创新成果,2006.101排名  

    7)中国国际工业博览会 银奖2010.081排名  

    8)(新加坡)陈金荣生命科学 科研成果 一等奖2004.011排名  

    9)中国科学技术发展基金会 首届十大青年科技成果奖,1994.10独立获奖

      

    教学成果

    (1) 苏豪杯第五届全国大学生蚕桑生物技术创新大赛 博士生组 特等奖2023,指导教师

    (2)第八届全国大学生生命科学竞赛(CULSC)创业组 二等奖2023,导教师

    (3)第八届全国大学生生命科学竞赛(CULSC)创新组 三等奖2023,指导教师

    (4)第九届江苏互联网+”大学生创新创业大赛 高教主赛道 二等奖2023,指导教师

    (5)第九届江苏省互联网+”大学生创新创业大赛 产业赛道 二等奖2023,指导教师

    (6)第四届江苏省大学生创业计划竞赛 特等奖2006,指导教师

    (7)第五届“挑战杯”中国大学生创业计划竞赛 银奖2006,指导教师 

    (8)第九届“挑战杯”全国大学生科技作品 一等奖2005,指导教师

    (9)首届江苏省优秀本专科毕业论文(设计)一等奖2005,指导教师  

    (10)江苏省高等教育教学成果奖 二等奖20011排名 

     

    荣誉称号  

    1)江苏省333高层次人才培养工程”首批中青年学科带头人培养对象,20072002  

    2)江苏省六大高峰人才,2005  

    3)苏州市 “一带一路”建设十周年 突出贡献奖,2023

    (4)苏州市 优秀共产党员,1993  

    (5)江苏省 青蓝工程 优秀教师获得者,1992